Fluids or Vasopressors for Haemodynamic Resuscitation in Septic Shock

Wednesday, March 8, 2023  |  1:00-2:00pm

Intravenous fluid resuscitation is established first line treatment for sepsis-associated hypoperfusion. The rationale is to correct hypovolemia and optimize stroke volume. Over the past decade evidence has emerged of harm associated with excess positive fluid balance in ICU patients with septic shock. Clinical trials undertaken in Africa have indicated harm from aggressive initial volume resuscitation but translating these results to other settings is problematic. The Surviving Sepsis Campaign has recently downgraded their recommendation for at least 30ml/kg of IV crystalloid to be administered for resuscitation in septic shock citing a paucity of evidence to support this practice. The uncertainty has led to some clinicians favoring the earlier introduction of vasopressors as a fluid sparing strategy. The effect on clinical outcomes is unclear and is this is the subject of ongoing international trials.

Speaker: Dr. Stephen MacDonald, BSc MBChB PhD DCH FRCPE FACEM; WA Health/Raine Clinician Research Fellow; Staff Specialist Emergency Medicine, Royal Perth Hospital, Clinical Associate Professor, Medical School, University of Western Australia, Adjunct Research Fellow, School of Public Health and Preventive Medicine, Monash University

View the event poster here

Location: DHCC 2267
Zoom link: https://ubc.zoom.us/ and click on ‘Join a Meeting’
Meeting ID: 91318 343657  Passcode: 343657